Natural gas pressure reduction stations experience significant temperature drops due to the Joule-Thompson effect as the gas pressure decreases from approximately 1000 to 250 psia, which can cause hydrate formation, gas condensate, corrosion, and equipment blockage. In this study, the steady-state performance of the Borujerd Qaleh-Hatam station was simulated using Aspen-HYSYS software, the Peng-Robinson equation of state, and the CSM Hydrate model. Five operational scenarios were evaluated from a technical and economic perspective, including heater removal at high inlet temperatures, heater replacement with a shell-and-tube heat exchanger, ethylene glycol removal, energy recovery with an expansion turbine, and the use of multiple regulators in series or parallel. The results showed that at inlet temperatures above 21°C, heater removal is feasible without the risk of hydrate formation and saves approximately 63 billion rials(B-IRR) annually. Replacing the heater with a shell-and-tube exchanger also results in an annual savings of 130 B-IRR with an investment of 130 B-IRR and a payback period of about one year. The largest savings are related to the expansion turbine, which, with an investment of 5,000 B-IRR, has reduced costs by 2,600 B-IRR annually and was introduced as the best long-term option. It is also possible to eliminate ethylene-glycol by monitoring the outlet temperature above 5 °C, but the use of multiple regulators in series or parallel is not technically and economically justified. Overall, the combination of an expansion turbine and a shell-and-tube exchanger is recommended as an optimal solution for simultaneously reducing energy consumption, chemicals, and operating costs.