Molecular imprinted polymer adsorbent is a new material that has attracted attention in the water treatment industry. In this study, a molecular imprinted polymer adsorbent based on a core/shell structure was successfully synthesized to be used for the removal of nickel ions from aqueous media. Magnetite nanoparticles (Fe3O4) were synthesized by co-precipitation method and then the core/shell structure of magnetite silica (Fe3O4@SiO2) was synthesized and after functionalization with an amino group, it was used as a basis for the synthesis of molecular imprinted polymer adsorbent (Fe3O4@SiO2-MIP). The molecular imprinted polymer adsorbent was synthesized in the presence of nickel target ion, Methacrylic acid monomer, initiator and crosslinker by in situ polymerization method. FTIR, XRD, TEM, FE-SEM, BET and VSM tests were used to determine the structure and properties of magnetite nanoparticles, core/shell structure and molecular imprinted polymer adsorbent. Also, adsorption tests were performed including the dose of the adsorbent, pH, initial concentration, isotherm, kinetics and selective adsorption. The results of the tests to determine the properties showed the presence of a magnetic phase and a core-shell structure. Also, the specific surface area and good magnetic properties were observed for the molecular imprinted polymer adsorbent. The optimal adsorption conditions were obtained including the adsorbent dose of 16 mg, pH 7 and the initial nickel concentration of 25 mg/l. The results of the adsorption tests showed that the maximum adsorption capacity of 105.26 mg/g was obtained for the molecular imprinted polymer adsorbent for nickel removal.