تعیین نرخ انتقال اکسیژن در ریۀ ‌مصنوعی نوزاد به‌روش سامانۀ سولفیت

نوع مقاله : مقاله پژوهشی

نویسنده

استادیار مهندسی شیمی، دانشگاه ولی‌عصر(عج) رفسنجان

چکیده

مهم‌ترین شاخص در طراحی و ساخت ریۀ مصنوعی متشکل از غشا‌های‌توخالی، نرخ‌ انتقال اکسیژن (OTR) است. روش‌های تعیین OTR در ریۀ ‌مصنوعی پیچیده هستند و نیاز به حسگرها و ابزار بسیار دقیقی دارند. سیال‌هایی که برای تعیین OTR در ریۀ ‌مصنوعی استفاده شده‌اند شامل خون، آب و مخلوط آب و گلیسرول هستند که هریک نقص‌ها و مشکلات به‌کارگیری متعددی دارند. در این مقاله سامانۀ سولفیت3 (SS) به‌عنوان سیالی که می‌تواند جای‌گزین خون در تعیین OTR باشد و مشکلات خون و نیاز به روابط و ابزار خاص نداشته باشد، در نظر گرفته می‌شود. به این منظور ابتدا شرایط OTR در ریۀ ‌مصنوعی با تعیین غلظت مناسب کاتالیزور(کبالت) در SS (دبی mL/min 2000 ( گاز و محلول سولفیت)) بهینه می‌شود، سپس نتایج حاصل از SS در دبی‌های (mL/min 2000 -500) با داده‌های خون در ریۀ ‌مصنوعی، مقایسه می‌شود. نتایج نشان می‌دهد که OTR متوسط SS با OTR متوسط خون در دبی mL/min 2000 کمتر از 10% اختلاف دارد

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Determination of Oxygen Transfer Rate in an Neonatal Artificial Lung by Sulfite system Method

نویسنده [English]

  • H. Eghbali
Assistant Professor of Chemical Engineering, Vali-e-Asr University of Rafsanjan
چکیده [English]

The most important parameter in the design and fabrication of an artificial lung consisting of hollow membranes is the oxygen transfer rate (OTR). OTR determination methods in the artificial lung are complex and require highly accurate sensors and instruments. The fluids used to determine OTR in the artificial lung are blood, water, and a mixture of water and glycerol, each of which has multiple drawbacks and problems. In this paper, the sulfite system (SS) is considered as a fluid that can replace blood in determining OTR and does not have blood problems and the need for special relationships and tools. For this purpose, the OTR conditions in the artificial lung are first optimized by determining the appropriate concentration of catalyst (cobalt) in SS (flow (gas and sulfite solution) 2000 mL/min). The results of SS at a flow rate (500-2000 mL/min) are then compared with blood data in an artificial lung. The results show that the mean OTR of SS is less than 10% different from the mean OTR of blood at 2000 mL / min flow.

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مهندسی شیمی ایران
دوره 22، شماره 126 - شماره پیاپی 126
فروردین و اردیبهشت 1402
صفحه 82-95

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