مروری بر خواص و کاربردهای هیدروژل کیتوسان- وانیل

نوع مقاله : مقاله مروری

نویسندگان

1 دانشجوی کارشناسی ارشد مهندسی شیمی، دانشگاه ولی عصر(عج) رفسنجان

2 استادیار مهندسی شیمی، دانشگاه ولی عصر(عج) رفسنجان

چکیده

امروزه هیدروژل‌‌های کیتوسان به‌‌دلیل داشتن خواص زیست‌‌سازگاری، زیست‌‌تجدیدپذیری، ارزانی، ضدباکتریایی و غیر‌‌سمّی‌‌‌‌بودن، بسیار پرکاربرد هستند. برای تولید هیدروژل‌‌های کیتوسان، از مواد اتصال‌‌دهندۀ عرضی مختلفی استفاده می‌‌شود که اغلبِ آن‌‌ها سمّی و خطرناک هستند. با توجه به کاربردهای فراوان هیدروژل‌‌های کیتوسانی در پزشکی، دارورسانی، مهندسی بافت، صنایع غذایی و کشاورزی بهتر است که برای تولیدشان از اتصال‌‌دهنده‌‌‌‌های عرضی امن و غیرسمّی استفاده شود. وانیل، آلدئیدی طبیعی و غیرسمّی است که می‌‌تواند به‌‌عنوان اتصال‌‌دهندۀ عرضی، در تولید هیدروژل‌‌های کیتوسانی به کار رود. علاوه ‌‌بر این، وانیل باعث افزایش خواص ضدمیکروبی و مکانیکی هیدروژل کیتوسان می‌‌شود. در این مقاله، خصوصیات و کاربردهای مختلف ترکیب کیتوسان- وانیل ازجمله کاربرد در مواد ضدمیکروبی و ضدسرطان، دارورسانی، جذب یون‌‌های فلزی از آب، چسب زخم، مهندسی بافت، تولید عطر و پوشش‌‌های نگهدارندۀ مواد غذایی، محصولات کشاورزی و نساجی مرور می‌‌شود.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Investigation of Properties and Applications of Chitosan-Vanillin Hydrogels: A Review

نویسندگان [English]

  • M. Sadeghi 1
  • H. Eghbali 2
1 M. Sc. Student of Chemical Engineering, Vali-e-Asr University of Rafsanjan
2 Assistant Professor of Chemical Engineering, Vali-e-Asr University of Rafsanjan
چکیده [English]

Nowdays, chitosan hydrogels are widely used due to their biocompatibility, biodegradability, cheapness, antibacterial and non-toxic properties. Chitosan hydrogels are made of various crosslinkers, which most of them are toxic and hazardous. Due to many applications of the hydrogels in medicine, drug delivery, tissue engineering and food industry, it is better to use safe and non-toxic crosslinkers in order to produce chitosan hydrogels. Vanilla is a natural and non-toxic aldehyde that can be used as a crosslinker. In addition, vanilla enhances the antimicrobial and mechanical properties of chitosan hydrogels. This paper reviews the various properties and applications of the chitosan-vanilla compound, including applications in antimicrobial and anticancer agents, drug delivery, metal ion absorption from water, perfume production and food preservatives and agricultural coatings.
 

کلیدواژه‌ها [English]

  • Chitosan
  • Vanillin
  • Hydrogel
  • antibacterial properties
  • Crosslinker
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