Application and importance of pH sensitive hydrogels in drug delivery

Articles in Press

Authors

1 Faculty of Chemical Engineering, Sahand University of Technology, Tabriz, Iran

2 Sahand University of Technology

10.22034/ijche.2023.404070.1329

Abstract

Hydrogels are water-insoluble three-dimensional networks that have the ability to absorb a lot of water in the biological environment. One of the most important characteristics of hydrogels is their reversible response to various stimuli, including pH, which causes the application and importance of hydrogel in various medical fields, such as contact lenses, tissue engineering, release of therapeutic agents, wound dressings, etc. Today, improving the effectiveness and safety ratio of existing drugs is an important challenge instead of developing new drugs that require a lot of money and time. The effectiveness of drugs is affected by a number of factors such as their low solubility in water, the risk of destruction in acidic environments, uneven absorption, low penetration of drugs, systematic side effects, etc. The drug has been effective. Therefore, the aim of this study is to investigate the role of pH-sensitive hydrogels in drug delivery, mechanism, swelling and drug release by these hydrogels.

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Iranian Chemical Engineering Journal

Articles in Press, Accepted Manuscript
Available Online from 13 November 2023

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