Optimization on operating condition for amino acids extraction by supercritical carbon dioxide

Document Type : Original Article

Authors

1 Department of chemical engineering- science and research branch- iau - tehran

2 Assistant Professor of Chemical Engineering, Science and Research Branch, Islamic Azad University, Tehran

3 Associate Professor of Chemical Engineering, Islamic Azad University of Marvdasht

4 Assistant Professor of Chemical Engineering, Faculty of Engineering, South Tehran Branch, Islamic Azad University, Tehran

5 Associate Professor of Chemical Engineering,Islamic Azad University of Marvdasht

10.22034/ijche.2023.404055.1328

Abstract

Abstract:

This research aimed to investigate optimum operating condition for selective extraction of free amino acids by supercritical carbon dioxide (SFE). OVAT experiment design technique is used, setting temperature and pressure as variables and setting time at 60 minute as constant. Results show that SFE has good efficiency in extraction of alanine, glycine, serine, glutamic acid and histidine while showing unsatisfactory results on others under the chosen operating conditions for this study. Experimental extraction results are plots in excel software which shows maximum selectivity and yield for glutamic acids at (P=14 Mpa T=20 0C) and for glycine at (P=16 Mpa T=60 0C) and for alanine, serine and histidine at (P=20 Mpa T=60 0C). The highest extraction yield (3.5%) was achieved at conditions where glutamic acid, the most abundant amino acid in the sample, had the highest exaction yield.

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